Health Content - Cancer

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Cancer
 

What is Cancer?

Cancer refers to any one of a large number of diseases characterized by the development of abnormal cells that divide uncontrollably and have the ability to enter (infiltrate) and destroy the other normal body tissues. Cancer also has the ability to spread throughout your body.

Cancer is one of the leading causes of death in the world. But survival rates are improving for many types of cancer thanks to improvements in cancer screening and cancer treatment.

Cancer is caused by damage (mutations) to the DNA within cells. Your DNA contains a set of instructions for your cells, telling them how to grow and divide. Normal cells often develop mutations in their DNA, but they have the ability to repair most of these mutations. Or, if they can't make the repairs, the cells often die. However, certain mutations aren't repaired, causing the cells to grow and become cancerous. Mutations also cause cancer cells to live beyond their normal cell life span. This causes the cancerous cells to accumulate.

In some cancers, accumulating cells form a tumor. But not all cancers form tumors. For example, leukemia is a cancer that involves blood, bone marrow, the lymphatic system and the spleen, but doesn't form a single mass or tumor.

Your genetic makeup, forces within your body, your lifestyle choices and your environment can all set the stage for cancer or help complete the process once it's started. For instance, if you've inherited a genetic mutation that predisposes you to cancer, you may be more likely than other people to develop cancer when exposed to a certain cancer-causing substance. The genetic mutation begins the cancer process, and the cancer-causing substance could play a role in further cancer development. Likewise, smokers who work with asbestos are more likely to develop lung cancer than are smokers who don't work with asbestos. That's because tobacco smoke and asbestos both play roles in cancer development.

What are the common signs and symptoms of cancer?

The signs and symptoms caused by cancer will vary depending on what part or organ of the body is affected.


Some general signs and symptoms associated with, but not specific to, cancer include:

  • Fatigue
  • Fever
  • Lump or thickening that can be felt under the skin
  • Pain
  • Weight changes, including unintended loss or gain
  • Skin changes, such as yellowing, darkening or redness of the skin, sores that won't heal, or changes to existing moles
  • Changes in bowel or bladder habits
  • Persistent cough
  • Difficulty swallowing
  • Hoarseness in voice
  • Persistent indigestion or discomfort after eating

What can one do to prevent cancer?

What do I and my family need to know or do if I have cancer?